I have found why this happens. Certain file cleaners (in my case it was
System Mechanic's "junk file" cleaner) DELETE the file OPA11.BAK. This file
is needed by Office for its activation/validation process, which is checked
everytime any Office product is run...at least in Office 2003 and 2007.
Then if you run a registry cleaner afterwards, the corresponding key in
HKLM\SOFTWARE\Microsoft\Office\(11.0 or 12.0)\Common\General\Data is deleted
as invalid.
If you reinstall the file and the registry key your Office will run like
before.
Oh. be sure to modify your file cleaner to NOT delete *.BAK files!!!
Cheers!
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